{"id":2474,"date":"2025-12-18T09:33:37","date_gmt":"2025-12-18T02:33:37","guid":{"rendered":"https:\/\/naviva.com.vn\/?p=2474"},"modified":"2025-12-18T09:33:37","modified_gmt":"2025-12-18T02:33:37","slug":"cac-cai-tien-quan-trong-voi-vac-xin-barycela-chia-khoa-dat-who-pq","status":"publish","type":"post","link":"https:\/\/tbyt.devjournal.io.vn\/index.php\/cac-cai-tien-quan-trong-voi-vac-xin-barycela-chia-khoa-dat-who-pq\/","title":{"rendered":"C\u00e1c c\u1ea3i ti\u1ebfn quan tr\u1ecdng v\u1edbi v\u1eafc xin Barycela &#8211; Ch\u00eca kh\u00f3a \u0111\u1ea1t WHO-PQ"},"content":{"rendered":"<p><span style=\"font-size: 14pt; font-family: 'times new roman', times, serif; color: #000000;\">C\u1ea3i ti\u1ebfn quy tr\u00ecnh s\u1ea3n xu\u1ea5t \u0111\u1ec3 n\u00e2ng cao ch\u1ea5t l\u01b0\u1ee3ng v\u1eafc xin \u0111\u1ea1t ch\u1ee9ng nh\u1eadn WHO-PQ &#8211; b\u00e0i h\u1ecdc t\u1eeb v\u1eafc xin th\u1ee7y \u0111\u1eadu\u00a0<a style=\"color: #000000;\" title=\"Barycela\" href=\"https:\/\/laodong.vn\/ldt\/suc-khoe\/vac-xin-thuy-dau-barycela-lua-chon-phu-hop-va-dang-tin-cay-1625070.ldo\" target=\"_self\" rel=\"noopener\">Barycela<\/a>\u00a0c\u1ee7a GC Biopharma (H\u00e0n Qu\u1ed1c).<\/span><\/p>\n<p><a href=\"https:\/\/tbyt.devjournal.io.vn\/wp-content\/uploads\/2025\/12\/7673B174-F620-4F9e-8.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2475\" src=\"https:\/\/tbyt.devjournal.io.vn\/wp-content\/uploads\/2025\/12\/7673B174-F620-4F9e-8.jpg\" alt=\"\" width=\"2000\" height=\"714\" \/><\/a><\/p>\n<p style=\"text-align: center;\"><span style=\"font-family: 'times new roman', times, serif;\">Quy tr\u00ecnh s\u1ea3n xu\u1ea5t v\u1eafc xin th\u1ee7y \u0111\u1eadu Barycela hi\u1ec7n \u0111\u1ea1i \u0111\u1ea1t WHO-PQ t\u1ea1i GC Biopharma. \u1ea2nh: NAVIVA Group<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">Ch\u1ee9ng nh\u1eadn Ti\u1ec1n th\u1ea9m \u0111\u1ecbnh c\u1ee7a T\u1ed5 ch\u1ee9c Y t\u1ebf Th\u1ebf gi\u1edbi (WHO Prequalification \u2013 WHO-PQ) \u0111\u01b0\u1ee3c xem nh\u01b0 \u201ct\u1ea5m h\u1ed9 chi\u1ebfu v\u00e0ng\u201d, kh\u1eb3ng \u0111\u1ecbnh ch\u1ea5t l\u01b0\u1ee3ng, an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 c\u1ee7a v\u1eafc xin, \u0111\u1ed3ng th\u1eddi m\u1edf ra c\u00e1nh c\u1eeda ti\u1ebfp c\u1eadn th\u1ecb tr\u01b0\u1eddng to\u00e0n c\u1ea7u, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh mua s\u1eafm c\u1ee7a Li\u00ean H\u1ee3p Qu\u1ed1c, UNICEF v\u00e0 nhi\u1ec1u t\u1ed5 ch\u1ee9c qu\u1ed1c t\u1ebf.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">V\u1eafc xin l\u00e0 ch\u1ebf ph\u1ea9m sinh h\u1ecdc \u0111\u1eb7c bi\u1ec7t, \u0111\u00f2i h\u1ecfi \u0111i\u1ec1u ki\u1ec7n s\u1ea3n xu\u1ea5t v\u00f4 tr\u00f9ng \u1edf m\u1ee9c cao nh\u1ea5t. C\u00e1c y\u00eau c\u1ea7u v\u1ec1 th\u1ef1c h\u00e0nh s\u1ea3n xu\u1ea5t t\u1ed1t (GMP) WHO li\u00ean t\u1ee5c \u0111\u01b0\u1ee3c c\u1eadp nh\u1eadt, trong \u0111\u00f3 n\u1ed5i b\u1eadt l\u00e0 t\u00e0i li\u1ec7u k\u1ef9 thu\u1eadt v\u1ec1 s\u1ea3n xu\u1ea5t d\u01b0\u1ee3c ph\u1ea9m v\u00f4 tr\u00f9ng (WHO.TRS 1044. ph\u1ee5 l\u1ee5c 2) ban h\u00e0nh n\u0103m 2022 [1]. Nh\u1eefng quy \u0111\u1ecbnh n\u00e0y \u0111\u1eb7t ra th\u00e1ch th\u1ee9c kh\u00f4ng nh\u1ecf cho c\u00e1c nh\u00e0 s\u1ea3n xu\u1ea5t v\u1eafc xin:<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">&#8211; Nh\u00e0 x\u01b0\u1edfng v\u00e0 thi\u1ebft b\u1ecb: ph\u1ea3i \u0111\u00e1p \u1ee9ng y\u00eau c\u1ea7u s\u1ea3n xu\u1ea5t kh\u00e9p k\u00edn, t\u1ef1 \u0111\u1ed9ng h\u00f3a cao, \u0111\u1eb7c bi\u1ec7t \u1edf kh\u00e2u \u0111\u00f3ng \u1ed1ng v\u00f4 tr\u00f9ng.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">&#8211; Quy tr\u00ecnh s\u1ea3n xu\u1ea5t c\u1ea7n gi\u1ea3m t\u1ed1i \u0111a thao t\u00e1c th\u1ee7 c\u00f4ng, t\u0103ng c\u01b0\u1eddng ki\u1ec3m so\u00e1t nguy c\u01a1 \u00f4 nhi\u1ec5m.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">&#8211; Nh\u00e2n s\u1ef1 ph\u1ea3i c\u00f3 tr\u00ecnh \u0111\u1ed9 cao, \u0111\u01b0\u1ee3c \u0111\u00e0o t\u1ea1o chuy\u00ean s\u00e2u, h\u1ea1n ch\u1ebf s\u1ed1 l\u01b0\u1ee3ng ng\u01b0\u1eddi tham gia tr\u1ef1c ti\u1ebfp.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">&#8211; Ngu\u1ed3n nguy\u00ean li\u1ec7u ph\u1ea3i \u0111\u1ea1t chu\u1ea9n qu\u1ed1c t\u1ebf v\u00e0 \u0111\u01b0\u1ee3c chu\u1ea9n h\u00f3a \u0111\u1ed3ng b\u1ed9.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">Vi\u1ec7t Nam \u0111ang s\u1edf h\u1eefu nhi\u1ec1u l\u1ee3i th\u1ebf \u0111\u1ec3 ti\u1ebfp c\u1eadn ch\u1ee9ng nh\u1eadn WHO-PQ. C\u01a1 quan qu\u1ea3n l\u00fd d\u01b0\u1ee3c qu\u1ed1c gia (NRA) c\u1ee7a Vi\u1ec7t Nam \u0111\u00e3 \u0111\u01b0\u1ee3c WHO c\u00f4ng nh\u1eadn, kh\u1eb3ng \u0111\u1ecbnh h\u1ec7 th\u1ed1ng qu\u1ea3n l\u00fd d\u01b0\u1ee3c v\u1eadn h\u00e0nh \u1ed5n \u0111\u1ecbnh, hi\u1ec7u qu\u1ea3 [2].<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">C\u00f9ng v\u1edbi \u0111\u00f3, Vi\u1ec7t Nam hi\u1ec7n \u0111\u00e3 l\u00e0m ch\u1ee7 c\u00f4ng ngh\u1ec7 s\u1ea3n xu\u1ea5t nhi\u1ec1u lo\u1ea1i v\u1eafc xin ti\u1ec1m n\u0103ng n\u1eb1m trong danh m\u1ee5c WHO \u01b0u ti\u00ean ti\u1ec1n th\u1ea9m \u0111\u1ecbnh, nh\u01b0 v\u1eafc xin s\u1edfi, v\u1eafc xin ph\u1ed1i h\u1ee3p s\u1edfi &#8211; rubella, v\u1eafc xin ph\u00f2ng ti\u00eau ch\u1ea3y c\u1ea5p do virus rota, v\u1eafc xin BCG v\u00e0 v\u1eafc xin vi\u00eam gan B [3].<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">C\u00e1c v\u1eafc xin n\u00e0y c\u1ee7a Vi\u1ec7t Nam \u0111\u1ec1u c\u00f3 c\u00e1c y\u00eau c\u1ea7u v\u1ec1 ch\u1ea5t l\u01b0\u1ee3ng qu\u1ed1c t\u1ebf t\u01b0\u01a1ng t\u1ef1 nh\u01b0 v\u1eafc xin th\u1ee7y \u0111\u1eadu Barycela c\u1ee7a GC Biopharma, m\u1ed9t v\u1eafc xin sau khi \u00e1p d\u1ee5ng c\u00e1c c\u1ea3i ti\u1ebfn v\u1ec1 quy tr\u00ecnh s\u1ea3n xu\u1ea5t \u0111\u1ec3 n\u00e2ng cao ch\u1ea5t l\u01b0\u1ee3ng s\u1ea3n ph\u1ea9m \u0111\u00e3 \u0111\u1ea1t ngay ch\u1ee9ng nh\u1eadn ti\u1ec1n th\u1ea9m \u0111\u1ecbnh WHO-PQ.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">GC Biopharma (H\u00e0n Qu\u1ed1c) \u0111\u00e3 ph\u00e1t tri\u1ec3n th\u00e0nh c\u00f4ng v\u00e0 \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p v\u1eafc xin th\u1ee7y \u0111\u1eadu s\u1ed1ng, gi\u1ea3m \u0111\u1ed9c l\u1ef1c t\u1eeb ch\u1ee7ng MAV\/06 &#8211; v\u1eafc xin th\u1ebf h\u1ec7 1 t\u1eeb n\u0103m 1993. V\u1eafc xin l\u01b0u h\u00e0nh t\u1ea1i nhi\u1ec1u qu\u1ed1c gia tr\u00ean th\u1ebf gi\u1edbi v\u1edbi t\u00ean th\u01b0\u01a1ng m\u1ea1i l\u00e0 Varicella v\u00e0 \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p t\u1ea1i Vi\u1ec7t Nam t\u1eeb n\u0103m 2008.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">V\u1eafc xin Varicella \u0111\u00e3 ch\u1ee9ng minh t\u00ednh an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 ph\u00f2ng b\u1ec7nh th\u1ee7y \u0111\u1eadu qua nhi\u1ec1u n\u0103m s\u1eed d\u1ee5ng. Tr\u01b0\u1edbc nh\u1eefng y\u00eau c\u1ea7u ng\u00e0y c\u00e0ng nghi\u00eam ng\u1eb7t c\u1ee7a WHO c\u0169ng nh\u01b0 ti\u00eau chu\u1ea9n cao c\u1ee7a c\u00e1c qu\u1ed1c gia nh\u1eadp kh\u1ea9u v\u1eafc xin, h\u01b0\u1edbng t\u1edbi vi\u1ec7c \u0111\u1ea1t \u0111\u01b0\u1ee3c ch\u1ee9ng nh\u1eadn ch\u1ea5t l\u01b0\u1ee3ng ti\u1ec1n th\u1ea9m \u0111\u1ecbnh WHO-PQ l\u00e0 \u0111\u00edch \u0111\u1ebfn c\u1ee7a v\u1eafc xin th\u1ee7y \u0111\u1eadu c\u1ea3i ti\u1ebfn &#8211; v\u1eafc xin th\u1ebf h\u1ec7 2 \u2013 Barycela. GC Biopharma \u0111\u00e3 tri\u1ec3n khai m\u1ed9t ch\u01b0\u01a1ng tr\u00ecnh c\u1ea3i ti\u1ebfn to\u00e0n di\u1ec7n v\u00e0 li\u00ean t\u1ee5c \u2013 t\u1eeb nh\u00e0 x\u01b0\u1edfng, thi\u1ebft b\u1ecb \u0111\u1ebfn quy tr\u00ecnh s\u1ea3n xu\u1ea5t v\u00e0 nguy\u00ean li\u1ec7u \u0111\u1ea7u v\u00e0o.<\/span><\/p>\n<p><a href=\"https:\/\/tbyt.devjournal.io.vn\/wp-content\/uploads\/2025\/11\/vac-xin-thuy-dau-barycela-4.png\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2426\" src=\"https:\/\/tbyt.devjournal.io.vn\/wp-content\/uploads\/2025\/11\/vac-xin-thuy-dau-barycela-4.png\" alt=\"\" width=\"3924\" height=\"2900\" \/><\/a><\/p>\n<p style=\"text-align: center;\"><span style=\"font-family: 'times new roman', times, serif;\">Barycela l\u00e0 v\u1eafc xin th\u1ee7y \u0111\u1eadu th\u1ebf h\u1ec7 m\u1edbi do GC Biopharma (H\u00e0n Qu\u1ed1c) s\u1ea3n xu\u1ea5t \u1ea2nh: NAVIVA Group<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">C\u00e1c c\u1ea3i ti\u1ebfn quan tr\u1ecdng v\u1edbi v\u1eafc xin th\u1ee7y \u0111\u1eadu th\u1ebf h\u1ec7 2 &#8211; Barycela &#8211; Ch\u00eca kh\u00f3a \u0111\u1ea1t WHO-PQ \u0111\u00f3 l\u00e0:<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">&#8211; T\u1ef1 \u0111\u1ed9ng h\u00f3a v\u00e0 c\u00f4ng ngh\u1ec7 s\u1eed d\u1ee5ng m\u1ed9t l\u1ea7n (single-use): To\u00e0n b\u1ed9 d\u00e2y chuy\u1ec1n tinh ch\u1ebf, \u0111\u00f3ng \u1ed1ng, \u0111\u00f4ng kh\u00f4 ho\u00e0n to\u00e0n t\u1ef1 \u0111\u1ed9ng, kh\u00e9p k\u00edn; \u00e1p d\u1ee5ng c\u00f4ng ngh\u1ec7 single-use (SUT) s\u1eed d\u1ee5ng c\u00e1c thi\u1ebft b\u1ecb ti\u1ebfp x\u00fac tr\u1ef1c ti\u1ebfp v\u1edbi s\u1ea3n ph\u1ea9m ch\u1ec9 d\u00f9ng m\u1ed9t l\u1ea7n trong c\u00e1c giai \u0111o\u1ea1n nu\u00f4i c\u1ea5y t\u1ebf b\u00e0o, g\u00e2y nhi\u1ec5m, nh\u00e2n virus v\u00e0 thu ho\u1ea1ch. \u0110i\u1ec1u n\u00e0y gi\u00fap gi\u1ea3m ti\u1ebfp x\u00fac con ng\u01b0\u1eddi, h\u1ea1n ch\u1ebf nguy c\u01a1 nhi\u1ec5m ch\u00e9o v\u00e0 lo\u1ea1i b\u1ecf ho\u00e0n to\u00e0n vi\u1ec7c s\u1eed d\u1ee5ng kh\u00e1ng sinh trong quy tr\u00ecnh s\u1ea3n xu\u1ea5t, h\u01b0\u1edbng t\u1edbi t\u00ednh an to\u00e0n t\u1ed1i \u01b0u cho s\u1ea3n ph\u1ea9m, gi\u1ea3m nguy c\u01a1 d\u1ecb \u1ee9ng \u1edf ng\u01b0\u1eddi \u0111\u01b0\u1ee3c ti\u00eam v\u1eafc xin.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">&#8211; N\u00e2ng cao \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh s\u1ea3n ph\u1ea9m: B\u1ed5 sung Ur\u00ea trong qu\u00e1 tr\u00ecnh pha tr\u1ed9n gi\u00fap duy tr\u00ec hi\u1ec7u gi\u00e1 virus \u1ed5n \u0111\u1ecbnh h\u01a1n khi bi\u1ebfn \u0111\u1ed9ng nhi\u1ec7t \u0111\u1ed9 trong s\u1ea3n xu\u1ea5t, v\u1eadn chuy\u1ec3n v\u00e0 b\u1ea3o qu\u1ea3n. Hi\u1ec7u gi\u00e1 t\u1ed1i thi\u1ec3u cu\u1ed1i th\u1eddi h\u1ea1n b\u1ea3o qu\u1ea3n \u0111\u1ea1t \u2265 3.800 PFU, cao h\u01a1n \u0111\u00e1ng k\u1ec3 so v\u1edbi m\u1ee9c \u2265 1.400 PFU c\u1ee7a v\u1eafc xin th\u1ebf h\u1ec7 1.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">&#8211; Thay \u0111\u1ed5i d\u00f2ng t\u1ebf b\u00e0o s\u1ea3n xu\u1ea5t: Chuy\u1ec3n t\u1eeb d\u00f2ng t\u1ebf b\u00e0o LuMA sang d\u00f2ng t\u1ebf b\u00e0o MRC-5 &#8211; d\u00f2ng t\u1ebf b\u00e0o l\u01b0\u1ee1ng b\u1ed9i \u0111\u00e3 \u0111\u01b0\u1ee3c WHO c\u00f4ng nh\u1eadn, s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i v\u00e0 ph\u00f9 h\u1ee3p cho s\u1ea3n xu\u1ea5t quy m\u00f4 l\u1edbn, \u1ed5n \u0111\u1ecbnh v\u1ec1 di truy\u1ec1n.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">Nh\u1edd nh\u1eefng c\u1ea3i ti\u1ebfn n\u00e0y, v\u1eafc xin th\u1ee7y \u0111\u1eadu th\u1ebf h\u1ec7 2 t\u1eeb ch\u1ee7ng MAV\/06, v\u1edbi t\u00ean th\u01b0\u01a1ng m\u1ea1i Barycela \u0111\u00e3 ch\u00ednh th\u1ee9c \u0111\u01b0\u1ee3c WHO c\u1ea5p ch\u1ee9ng nh\u1eadn ti\u1ec1n th\u1ea9m \u0111\u1ecbnh (WHO-PQ) t\u1eeb n\u0103m 2023. \u0110\u1ebfn n\u0103m 2025, v\u1eafc xin \u0111\u01b0\u1ee3c c\u1ea5p ph\u00e9p l\u01b0u h\u00e0nh v\u00e0 s\u1eed d\u1ee5ng t\u1ea1i Vi\u1ec7t Nam v\u00e0 nhi\u1ec1u qu\u1ed1c gia kh\u00e1c nh\u01b0 Pakistan, Th\u1ed5 Nh\u0129 K\u1ef3, Ai C\u1eadp, Libya, Brazil\u2026<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">B\u00e0i h\u1ecdc t\u1eeb H\u00e0n Qu\u1ed1c kh\u1eb3ng \u0111\u1ecbnh, WHO-PQ kh\u00f4ng ph\u1ea3i l\u00e0 \u0111\u00edch \u0111\u1ebfn ng\u1eafn h\u1ea1n m\u00e0 l\u00e0 m\u1ed9t h\u00e0nh tr\u00ecnh d\u00e0i, \u0111\u00f2i h\u1ecfi t\u1ea7m nh\u00ecn chi\u1ebfn l\u01b0\u1ee3c, \u0111\u1ea7u t\u01b0 b\u00e0i b\u1ea3n v\u00e0 c\u1ea3i ti\u1ebfn li\u00ean t\u1ee5c. Chu\u1ea9n h\u00f3a nguy\u00ean li\u1ec7u, n\u00e2ng c\u1ea5p nh\u00e0 x\u01b0\u1edfng, hi\u1ec7n \u0111\u1ea1i h\u00f3a thi\u1ebft b\u1ecb v\u00e0 x\u00e2y d\u1ef1ng h\u1ec7 th\u1ed1ng qu\u1ea3n l\u00fd ch\u1ea5t l\u01b0\u1ee3ng to\u00e0n di\u1ec7n ch\u00ednh l\u00e0 nh\u1eefng y\u1ebfu t\u1ed1 then ch\u1ed1t.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">Kh\u00f4ng ch\u1ec9 nh\u1eb1m \u201c\u0111\u1ea1t chu\u1ea9n WHO\u201d, khi \u00e1p d\u1ee5ng \u0111\u01b0\u1ee3c nh\u1eefng c\u1ea3i ti\u1ebfn n\u00e0y s\u1ebd gi\u00fap n\u00e2ng cao ch\u1ea5t l\u01b0\u1ee3ng v\u1eafc xin Vi\u1ec7t Nam, gi\u1ea3m r\u1ee7i ro s\u1ea3n xu\u1ea5t, t\u0103ng kh\u1ea3 n\u0103ng c\u1ea1nh tranh qu\u1ed1c t\u1ebf v\u00e0 m\u1edf r\u1ed9ng c\u01a1 h\u1ed9i xu\u1ea5t kh\u1ea9u. Quan tr\u1ecdng h\u01a1n, \u0111\u00f3 l\u00e0 b\u01b0\u1edbc \u0111i c\u1ea7n thi\u1ebft \u0111\u1ec3 v\u1eafc xin Vi\u1ec7t Nam kh\u1eb3ng \u0111\u1ecbnh v\u1ecb th\u1ebf tr\u00ean b\u1ea3n \u0111\u1ed3 c\u00f4ng nghi\u1ec7p v\u1eafc xin to\u00e0n c\u1ea7u.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">1. WHO, WHO good manufacturing practices for sterile pharmaceutical products, Annex 2, WHO Technical Report Series 1044, 2022, https:\/\/www.who.int\/publications\/m\/item\/trs1044-annex2, ng\u00e0y truy c\u1eadp 14\/12\/2025<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">2. WHO, List of National Regulatory Authorities (NRAs) operating at maturity level 3 (ML3) and maturity level 4 (ML4), https:\/\/www.who.int\/publications\/m\/item\/list-of-nras-operating-at-ml3-and-ml4, ng\u00e0y truy c\u1eadp 14\/12\/2025<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">3. WHO, Vaccines Prequalification Priority List 2024 \u2013 2026, https:\/\/extranet.who.int\/prequal\/vaccines\/vaccines-eligible-who-prequalification, ng\u00e0y truy c\u1eadp 14\/12\/2025<\/span><\/p>\n<div class=\"box-fullwidth\">\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">V\u1eafc xin th\u1ee7y \u0111\u1eadu BARYCELA Inj. \u0111\u1ea1t ch\u1ee9ng nh\u1eadn WHO-PQ \u0111\u00e3 \u0111\u01b0\u1ee3c ph\u00e2n ph\u1ed1i t\u1ea1i Vi\u1ec7t Nam b\u1edfi c\u00f4ng ty NAVIVA GROUP<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">&#8211; Lo\u1ea1i b\u1ecf ho\u00e0n to\u00e0n vi\u1ec7c s\u1eed d\u1ee5ng kh\u00e1ng sinh trong quy tr\u00ecnh s\u1ea3n xu\u1ea5t, t\u0103ng t\u00ednh an to\u00e0n, gi\u1ea3m nguy c\u01a1 d\u1ecb \u1ee9ng \u1edf ng\u01b0\u1eddi \u0111\u01b0\u1ee3c ti\u00eam v\u1eafc xin.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">&#8211; Hi\u1ec7u gi\u00e1 v\u1eafc xin t\u1ed1i thi\u1ec3u \u1edf cu\u1ed1i th\u1eddi h\u1ea1n b\u1ea3o qu\u1ea3n \u0111\u1ea1t \u0111\u1ebfn \u2265 3.800 PFU, cao nh\u1ea5t trong c\u00e1c lo\u1ea1i v\u1eafc xin th\u1ee7y \u0111\u1eadu \u0111ang \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh t\u1ea1i Vi\u1ec7t Nam hi\u1ec7n nay.<\/span><\/p>\n<p><span style=\"color: #000000; font-size: 14pt; font-family: 'times new roman', times, serif;\">S\u1eed d\u1ee5ng d\u00f2ng t\u1ebf b\u00e0o MRC-5 &#8211; d\u00f2ng t\u1ebf b\u00e0o l\u01b0\u1ee1ng b\u1ed9i \u0111\u00e3 \u0111\u01b0\u1ee3c WHO c\u00f4ng nh\u1eadn.<\/span><\/p>\n<\/div>\n<p><span style=\"font-family: 'times new roman', times, serif;\">Ngu\u1ed3n:<a href=\"https:\/\/laodong.vn\/ldt\/suc-khoe\/cac-cai-tien-quan-trong-voi-vac-xin-barycela-chia-khoa-dat-who-pq-1626590.ldo\" target=\"_blank\" rel=\"noopener\"> B\u00e1o lao \u0111\u1ed9ng<\/a><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>C\u1ea3i ti\u1ebfn quy tr\u00ecnh s\u1ea3n xu\u1ea5t \u0111\u1ec3 n\u00e2ng cao ch\u1ea5t l\u01b0\u1ee3ng v\u1eafc xin \u0111\u1ea1t ch\u1ee9ng nh\u1eadn WHO-PQ &#8211; b\u00e0i h\u1ecdc t\u1eeb v\u1eafc xin th\u1ee7y \u0111\u1eadu\u00a0Barycela\u00a0c\u1ee7a GC Biopharma (H\u00e0n Qu\u1ed1c). Quy tr\u00ecnh s\u1ea3n xu\u1ea5t v\u1eafc xin th\u1ee7y \u0111\u1eadu Barycela hi\u1ec7n \u0111\u1ea1i \u0111\u1ea1t WHO-PQ t\u1ea1i GC Biopharma. \u1ea2nh: NAVIVA Group Ch\u1ee9ng nh\u1eadn Ti\u1ec1n th\u1ea9m \u0111\u1ecbnh c\u1ee7a T\u1ed5 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":2475,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[59],"tags":[],"class_list":["post-2474","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-tin-tuc"],"acf":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/wp\/v2\/posts\/2474","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/wp\/v2\/comments?post=2474"}],"version-history":[{"count":0,"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/wp\/v2\/posts\/2474\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/"}],"wp:attachment":[{"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/wp\/v2\/media?parent=2474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/wp\/v2\/categories?post=2474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/tbyt.devjournal.io.vn\/index.php\/wp-json\/wp\/v2\/tags?post=2474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}